Common and unique components of inhibition and working memory: an fMRI, within-subjects investigation.

نویسندگان

  • Fiona McNab
  • Gaëlle Leroux
  • Fredrik Strand
  • Lisa Thorell
  • Sissela Bergman
  • Torkel Klingberg
چکیده

Behavioural findings indicate that the core executive functions of inhibition and working memory are closely linked, and neuroimaging studies indicate overlap between their neural correlates. There has not, however, been a comprehensive study, including several inhibition tasks and several working memory tasks, performed by the same subjects. In the present study, 11 healthy adult subjects completed separate blocks of 3 inhibition tasks (a stop task, a go/no-go task and a flanker task), and 2 working memory tasks (one spatial and one verbal). Activation common to all 5 tasks was identified in the right inferior frontal gyrus, and, at a lower threshold, also the right middle frontal gyrus and right parietal regions (BA 40 and BA 7). Left inferior frontal regions of interest (ROIs) showed a significant conjunction between all tasks except the flanker task. The present study could not pinpoint the specific function of each common region, but the parietal region identified here has previously been consistently related to working memory storage and the right inferior frontal gyrus has been associated with inhibition in both lesion and imaging studies. These results support the notion that inhibitory and working memory tasks involve common neural components, which may provide a neural basis for the interrelationship between the two systems.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Effectiveness of HAMRAH Cognitive Rehabilitation Package on Improving Executive Functions (Working Memory and Response Inhibition) in Students with Dysgraphia

Dysgraphia is one of the common symptoms of specific learning disorders. children with dysgraphia have several cognitive problems. This research was conducted with the aim of investigating the effectiveness of HAMRAH cognitive rehabilitation package on improving executive functions (working memory and response inhibition) in children with dysgraphia. The present research was semi-experimental i...

متن کامل

The Effectiveness of Computerized Cognitive Rehabilitation in Improving Response Inhibition and Working Memory in Adolescents with Tendency to Substance Use

Objective: The current study was conducted to determine the effectiveness of computerized cognitive rehabilitation in improving response inhibition and working memory in adolescents with tendency to substance use. Method: The research method was semi-experimental with a pre-test and post-test design with a control group. The study population included all 15-18-year-old adolescents living in Tab...

متن کامل

Comparing the Effectiveness of the Non- Soft Training Package of Working Memory and Selective Attention With Captain’s Log Cognitive Empowerment Software Package on the Components of the Working Memory in Girls With Temporal Lobe Epilepsy

Background and Objective: The purpose of this study was to compare the effectiveness of the non-computerized training package of working memory (WM) and selective attention with captain’s Log software on the components of WM. Materials and Methods: The present study was conducted in a quasi-experimental design, with non- random targeted sampling, and pre-test, post-test, follow-up, and control...

متن کامل

Effectiveness of working memory intervention in behavior inhibition and visual working memory of children with Attention Deficit/ impulsive subtype Disorder (ADHD-I)

The aim of the current research study was to determine the effectiveness of working memory intervention on behavioral inhibition and visual working memory in children with symptoms of attention-deficit/impulsivity disorder in Selseleh city. The method was a quasi-experimental pre-test-post-test design with a control group. The statistical population consisted of all boy students of 8-12 years o...

متن کامل

Comparison of the effect of Transcranial Direct Current Stimulation (tDCS (and Transcranial Random Noise Stimulation (tRNS (combined with cognitive training on working memory performance of people with attention deficit/hyperactivity disorder

This study aimed to comparison of the effect of Transcranial Direct Current Stimulation (tDCS) and Transcranial Random Noise Stimulation (tRNS) combined with cognitive training on working memory performance of people with attention deficit/hyperactivity disorder. For this purpose, 45 children with attention deficit hyperactivity disorder in zahedan city were purposefully selected as the researc...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Neuropsychologia

دوره 46 11  شماره 

صفحات  -

تاریخ انتشار 2008